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PIR4 is the least comprehensive, D. PrP mice injected with the RML scrapie isolate had incubation periods (400-465) more prolonged than the heterozygous Pm-paPm-pb mice (268 d) (23,24) and PrP infected with 30 1C isolate have mcubatron periods considerably shorter than the Pm-paPm-pb mice (Table 1).
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